American Heart Association: If you want email subscribers to respond to a call-to-action, you need to understand what motivates them. The problem is, different groups within your database have different motivators."

See how the marketing team at the American Heart Association solved this problem with a take on segmentation called "mind type." By researching its database and uncovering the key interest areas of four unique groups, the AHA created an email nurturing campaign that spoke directly to subscriber motivations and increased donation rates 42.5%.

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